Producción Científica

Background Myocardial ischemia-reperfusion injury (MIRI) is defined as the restoration of blood flow to the myocardium after a brief interruption of blood supply, causing more severe damage to the ischemic myocardium. However, currently, reperfusion therapy is the preferred therapy for ischemic cardiomyopathy, which undoubtedly causes MIRI, and thus it has become a challenging issue affecting the prognosis of coronary artery disease. Methods A search was conducted in the Web of Science Core Collection database for papers relevant to MIRI therapy published between 1 January 2000 and 1 October 2023. Bibliometric analyses were performed using VOSviewer and CiteSpace to elucidate the progress and hotspots. Results 3304 papers from 64 countries, 2134 research institutions and 13,228 authors were enrolled in the study. Of these, China contributed the most papers and had the biggest impact, while the United States had the most extensive partnership. The Fourth Military Medical University was the primary research institution. The most valuable authors include Chattipakorn, Nipon, Chattipakorn, Siriporn c, Yang, Jian and Yang, Yang. Conclusion Over the past 20 years, research on MIRI therapies has made significant strides. Further studies are necessary to explore the interactions between various therapeutic options. Future investigations will emphasize nanocarriers, cardiac regeneration, and stem cell therapies. Our study identifies MIRI research hotspots from a bibliometric perspective, forecasts future trends, and offers fresh insights into MIRI therapy research.

Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, but its diagnosis and treatment remain obscure. Non-coding RNAs (ncRNAs), as potential biomarkers, have attracted increasing attention in digestive diseases. Here, we present a comprehensive research status, development trends, and valuable insights in this subject area. The literature search was performed using Web of Science Core Collection. VOSviewer 1.6.20, Citespace 6.2.R4, and Microsoft Excel 2021 were used for bibliometric analysis. A total of 124 articles were included in the analysis. Overall, publication patterns fluctuated. Globally, People’s Republic of China, the USA, and Germany were the top three contributors of publications. Guangzhou University of Chinese Medicine, University of California, Mayo Clinic, and University of California, Los Angeles contributed the highest number of publications. The pathways and specific mechanisms by which ncRNAs regulate transcription and translation and thus regulate the pathophysiological processes of IBS are the main research hotspots in this field. We found that microRNA (miRNAs) are intricately involved in the regulation of key pathologies such as viscera sensitivity, intestinal permeability, intestinal mucosal barrier, immunoinflammatory response, and brain-gut axis in the IBS, and these topics have garnered significant attention in research community. Notably, microecological disorders are also associated with IBS pathogenesis, and ncRNA may play an important role in the interactions between host and intestinal flora. This is the first bibliometric study to comprehensively summarize the research hotspots and trends related to IBS and ncRNAs (especially miRNAs). Our findings will help understand the role of ncRNAs in IBS and provide guidance to future studies.

Background This bibliometric study aims to examine the associations of journals in the field of human reproduction with their access types and article processing charges to evaluate the evolving landscape of publishing in human reproduction. Methods The primary databases, including Clarivate Analytics Master Journal List, Scopus®, PubMed, and Directory of Open Access Journals, were scrutinized to identify pertinent journals within the realm of human reproduction, utilizing keywords such as reproductive, reproduction, fertility, and infertility. Journals were excluded if they were not actively publishing in English or primarily focused on reproductive health, men’s health, sexual medicine, embryogenesis, developmental biology, or veterinary medicine concerning animal reproduction. A thorough characterization of the journals was conducted, followed by a comparative analysis of citation metrics and article processing charges across various access models. Results Forty-one journals were included into the study. A significant increase in the proportion of gold and diamond open-access journals was observed, rising from 42% (13 out of 31) to 53.6% (22 out of 41) by 2023. Hybrid journals demonstrated superior citation metrics compared to diamond open-access journals. For hybrid journals, a statistically significant, moderately positive correlation was found between article processing charges and CiteScore (rs (27) = 0.515, p < .024). Conversely, no correlation was observed between article processing charges and CiteScore for gold open-access journals (rs (27) = 0.445, p = 0.147). The mean article processing charges for all hybrid and gold open-access journals were calculated as US $3032.88 ± 1108.514 (312 to 4430). Specifically, the mean article processing charges for hybrid journals (US $3617.4 ± 610.19) were significantly higher than those for gold open-access journals (US $1916.82 ± 988.32), with a difference of 1700.658 (95% CI: 1124.861–2276.455), t (30) = 6.032, and p < .0005. Conclusion Hybrid journals in the field of human reproduction carry fees nearly twice as high as those of gold open-access journals. The charging policies of gold open-access journals, which are not contigent upon citation metrics, emphasize the importance of caution for both authors and funders.