Producción Científica

Purpose: This bibliometric analysis of the top 100 cited articles on extended reality (XR) in neurosurgery aimed to reveal trends in this research field. Gender differences in authorship and global distribution of the most-cited articles were also addressed. Methods: A Web of Science electronic database search was conducted. The top 100 most-cited articles related to the scope of this review were retrieved and analyzed for trends in publications, journal characteristics, authorship, global distribution, study design, and focus areas. After a brief description of the top 100 publications, a comparative analysis between spinal and cranial publications was performed. Results: From 2005, there was a significant increase in spinal neurosurgery publications with a focus on pedicle screw placement. Most articles were original research studies, with an emphasis on augmented reality (AR). In cranial neurosurgery, there was no notable increase in publications. There was an increase in studies assessing both AR and virtual reality (VR) research, with a notable emphasis on VR compared to AR. Education, surgical skills assessment, and surgical planning were more common themes in cranial studies compared to spinal studies. Female authorship was notably low in both groups, with no significant increase over time. The USA and Canada contributed most of the publications in the research field. Conclusions: Research regarding the use of XR in neurosurgery increased significantly from 2005. Cranial research focused on VR and resident education while spinal research focused on AR and neuronavigation. Female authorship was underrepresented. North America provides most of the high-impact research in this area.

Background: Helicobacter pylori (H. pylori) infection is prevalent and associated with the development of various gastric diseases. On the other hand, inflammatory bowel disease (IBD) is an immune-related intestinal disorder influenced by factors like gut microbiota imbalance, genetic predisposition, and environmental influences. Despite extensive research on the H. pylori–IBD relationship, a comprehensive bibliometric analysis in this area is lacking. Therefore, this study aims to use bibliometric methods to explore research trends, hotspots, and frontiers in H. pylori and IBD-related research, offering valuable insights for future research and clinical practice. Methods: We retrieved relevant literature on H. pylori and IBD from the Web of Science Core Collection (WoSCC) and Scopus databases covering 2007 to 2024. We perform a comprehensive analysis within the WoSCC literature. We compare these findings with relevant results from Scopus. Results: Research on H. pylori and IBD has remained prominent in recent years. The United States leads in output, with strong contributions from authors, institutions, and journals. China, despite being a developing country, shows rapid article growth, signaling growing research potential. Key topics include Crohn’s disease, gut microbiota, H. pylori infection, and ulcerative colitis. Newer interests include health, cancer prevention, and chronic gastritis. Conclusion: Over the past, research on H. pylori and IBD has primarily centered around epidemiology and clinical studies. The question of whether H. pylori definitively offers protective effects against IBD remains unresolved. Therefore, further investigation could explore the underlying mechanisms of their relationship or initiate long-term prospective cohort studies to gather more compelling evidence.

Over the past decade, there has been a notable surge in research dedicated to unraveling the intricate role of tight junction proteinsin blood–brain barrier (BBB) damage associated with ischemic stroke. This bibliometric analysis explores the expansive landscapeof occludin research, a key tight junction protein, during the years 2000–2023, shedding light on the global scientific contributions,collaborations, and emerging trends in this critical area of stroke pathogenesis. China and the United States emerge as significantcontributors, underscoring their prominence in advancing our understanding of tight junction proteins. Occludin, identified as alinchpin in regulating BBB integrity, proves to be a pivotal player, with implications extending to the diagnosis of hemorrhagictransformation in ischemic stroke. This study identifies occludin as a potential biomarker, offering promise for early diagnosis andpaving the way for novel diagnostic strategies. The analysis highlights the necessity for a more comprehensive exploration of tightjunction proteins, including occludin and claudin-5, particularly in the context of acute cerebral ischemia. The unique healthcarelandscape in Kazakhstan adds urgency to the call for further scientific research in this region, emphasizing the need for tailoredinvestigations to address specific regional challenges. This comprehensive overview not only delineates the current state of occludinresearch but also signals the direction for future investigations. The identified knowledge gaps and emerging trends provide aroadmap for researchers and policymakers alike, with implications for both scientific discourse and clinical practice. Movingforward, a deeper understanding of tight junction proteins, informed by the insights gleaned from this study, holds the potential toshape targeted therapeutic interventions and diagnostic strategies, ultimately contributing to advancements in global stroke care.