Producción Científica

Background: Despite advancements in medical science, the 5-year survival rate for laryngeal squamous cell carcinoma remains low, posing significant challenges in clinical management. This study explores the evolution of key topics and trends in laryngeal cancer research. Bibliometric and knowledge graph analysis are utilized to assess contributions in treating this carcinoma and to forecast emerging research hotspots that may enhance future clinical outcomes. The findings aim to guide researchers by identifying new areas, providing valuable insights and innovative perspectives. Methods: Data were extracted from the Web of Science Core Collection database on December 1, 2023. Bibliometric and knowledge mapping analyses were conducted using software tools such as R-Studio 4.1.3, CiteSpace 6.1.R6, VOSviewer 1.6.18, and http://bibliometre.com.(Both CiteSpace 6.1.R6 and VOSviewer 1.6.18 are widely used bibliometric analysis software tools, each with distinct features and applications. CiteSpace primarily focuses on analyzing literature citation relationships and generating knowledge graphs to visualize research hotspots, trends, and knowledge structures. Its data sources include platforms such as Web of Science. While CiteSpace excels in presenting knowledge structures through its advanced visualization capabilities, it is relatively complex to operate and less efficient in processing large-scale datasets. As a result, it is frequently employed in exploring research trends across multiple disciplines. On the other hand, VOSviewer is designed to construct various types of bibliometric networks and is characterized by its intuitive and user-friendly interface. It supports a wide range of data sources and produces visually appealing and clear visualizations, making it particularly suitable for multi-disciplinary bibliometric research. Additionally, VOSviewer provides valuable insights that can inform scientific research decision-making. Overall, the two tools differ in terms of functionality, data sources, visualization effects, and operational complexity, offering researchers complementary options for bibliometric analysis based on their specific needs.) From this database, 800 papers were extracted using specific criteria. After narrowing the scope to English-language publications, this number was reduced to 775. To ensure data quality, conference papers, letters, and editorial materials were excluded, focusing only on original research papers and review articles. Results: The analysis showed that 760 theoretical works and review papers were published in 96 academic journals by 4210 authors from 1148 institutions across 60 countries/regions. The United States emerged as the most significant contributor to laryngeal cancer research. The Croatian Rudjer Boskovic Institute was notable for having the highest publication and citation counts. Among individual researchers, Osmak, M was identified as the most prolific and cited. Predominant international collaborations occurred between European and American countries. The Head and Neck Science Journal was the most frequently co-cited publication. Major research themes encompassed morphological aspects, chemotherapy, and molecular pathway mechanisms in laryngeal cancer treatment. Current research hotspots include disease prognosis, models, clinical trials, tumor recurrence, and surveillance. Notably, targeted therapy and immunotherapy are rapidly advancing fields. Conclusions: There is an urgent need to enhance global scholarly communication as the pursuit of effective laryngeal cancer treatment progresses. Focused research on targeting indicators for this type of cancer remains vital. An impending surge in research is driven by investigations into biomarkers, microenvironmental genetic mechanisms, alternatives to systemic chemotherapy, minimally invasive surgery, and herbal medicine explorations.

The incidence of polycystic ovary syndrome (PCOS) in women of reproductive age is increasing worldwide and no specific treatment is available for this. Nowadays, medicinal plants are highly considered as therapeutic agents for disease management due to their easy availability and less toxic nature but they have not received much attention for the treatment of PCOS. This study presents a comprehensive knowledge of medicinal plants for PCOS management and bibliometric analysis of data available in Scopus database to understand the research trends with reference to co-authorship network, collaborative countries, source of documents, and different keywords through VOSviewer software. Maximum plants studied in PCOS belongs to Leguminosae family, however, the most studied plant is Cinnamomum zeylanicum (Lauraceae) and the preferred extract was hydroalcoholic extract. Out of 294 documents, 212 comprise of in vivo studies, where 43.87 % experiments were letrozole-induced animal model. South East Asian countries are predominantly exploring medicinal plants for PCOS management as the prevalence of PCOS is high in this region. Overall, this study may help future researchers to understand the research gaps and can assist as a pocket dictionary of appraisal reports on the performance of natural products for the management of PCOS.

Background: Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a leading cause of end-stage renal disease worldwide. Understanding trends in experimental research on DN is crucial for advancing knowledge and clinical management. Objective: This study aimed to explore current trends in DN related experimental research, utilizing CiteSpace, VOSviewer, and Bibliometrix to identify key contributors, influential countries, and noteworthy topics. The objective was to provide valuable insights for healthcare professionals and researchers in the field. Methods: Relevant publications from the Web of Science Core Collection Science Citation Index Expanded were retrieved for the period between 2018 and 2024. CiteSpace, VOSviewer, and Bibliometrix were employed for data analysis, including identifying top authors, institutions, countries, keywords, co-cited authors, journals, references, and research trends. Results: A total of 1501 relevant articles were included in the study. DN related experimental research exhibited an upward trend, reaching its peak in 2023. Key contributors such as Kretzler Matthias, Li Ping, and Rossing Peter emerged. China, the United States and Japan have the most publications. Keyword analysis revealed “activated protein kinase” as the most central keyword, while “diabetic nephropathy” had the highest citation rate. Recent focus shifted towards keywords like “Traditional Chinese Medicine” and “molecular docking.” Conclusion: This bibliometric analysis provides insights into trends in experimental research on DN from 2018 to 2024. Notable contributors and influential countries were identified, emphasizing global collaboration. Key topics demonstrate diverse approaches and emerging trends, supporting informed decision-making and innovation in combatting DN and enhancing patient outcomes.