Producción Científica

The potential of paraprobiotics and postbiotics to be used as beneficial agents for human health has caused an effort by the scientific community to gather information about the bioactivity of these compounds and production methods. Understanding the evolution of scientific research in this area of study is important to understand the future perspectives and the main bottlenecks of scientific and technological development involving these compounds. In this scenario, this review work used a bibliometric analysis tool intending to improve the scientific documentation, bringing information and communicating the results to the scientific community through the quantitative analysis of the current literature, available in one of the main databases, the Web of Science, also providing recent information on the evolution and future perspectives in the field of paraprobiotic and postbiotic development. The results of this study showed that the main studies discuss the bioactivity of these compounds. Concerning the development of functional foods, there is a need for extensive research on production methods and the interaction of these compounds with food. However, it concluded that much still needs to be studied to prove the claims of bioactivity, especially when used for the development of functional foods.

Context: Because of the recent pandemic COVID-19, research on management systems health information grew rapidly, underscoring the importance of knowing the investigative trends in these issues to identify the findings and global networks knowledge. Aims: To examine the developments and research trends in information management in health. Methods: A bibliometric analysis was carried out with the 215 results obtained from a search equation performed in the Scopus database. Documents were selected using the inclusion criteria according to the recommendations of the international declaration PRISMA and calculation was performed indicators of quality, quantity, and trend analysis. Results: These were identified as trends: Managing information and knowledge, Educational model/Curriculum design, information-seeking behavior. A research agenda also arises with the themes: reconfiguration of health policies, design and collaborative use in digital resources, telemedicine, meta-analysis tools for decision-making and cloud infrastructures. Conclusions: The United States leads the production in the subject, but there is a gap in Latin America in research in this field of knowledge. Likewise, as new routes in which the research exercise should be deepened are the reconfiguration of health policies, design and collaborative use of digital resources, telemedicine, meta-analysis of tools for decision making and Cloud infrastructures.

Midazolam is a drug with actions towards the central nervous system producing sedative and anticonvulsants effects, used for sedation and seizures treatments. A better understanding about its effects in the different scenarios presented in the literature could be helpful to gather information regarding its clinical indications, pharmacological interactions, and adverse events. From this perspective, the aim of this study was to analyze the global research about midazolam mapping, specifically the knowledge of the 100 most-cited papers about this research field. For this, a search was executed on the Web of Science-Core Collection database using bibliometric methodological tools. The search strategy retrieved 34,799 articles. A total of 170 articles were evaluated, with 70 articles being excluded for not meeting the inclusion criteria. The 100 most-cited articles rendered 42,480 citations on WoS-CC, ranging from 253 to 1744. Non-systematic review was the most published study type, mainly from North America, during the period of 1992 to 2002. The most frequent keywords were midazolam and pharmacokinetics. Regarding the authors, Thummel and Kunze were the ones with the greatest number of papers included. Our findings showed the global research trends about midazolam, mainly related to its different effects and uses throughout the time.