Producción Científica

Focal therapy, a minimally invasive strategy for localized prostate cancer, has been widely employed in the targeted treatment of localized prostate cancer in recent years. We analyzed 1312 relevant papers from the last decade using Web of Science Core Collection data. Our analysis covered countries, institutions, journals, authors, keywords, and references to offer a multifaceted perspective on the development of this field. The U.S. led in publications, contributing over half of the top 10 institutions. Emberton, M from University College London was the most published and cited author. “EUROPEAN UROLOGY” was the top journal by impact factor in 2022. Analysis of references and keywords suggests the prevalence of brachytherapy-related research, while high-intensity focused ultrasound (HIFU), cryotherapy, and irreversible electroporation (IRE) are emerging as new research focuses. Consequently, more high-quality evidence is necessary to evaluate the long-term effectiveness and safety of these novel therapeutic methods.

Background: Over the past three decades, endoplasmic reticulum (ER) stress has gained considerable attention in the field of hepatocellular carcinoma (HCC) with an increasing number of publications. It is crucial to reveal the global status, research hotspots and future research trends of ER stress in HCC. The aim of this study is to analyze the publications related to ER stress in HCC through bibliometric analysis in order to better understand the current status of ER stress research in HCC and to identify potential new research directions. Methods: In this study, articles and reviews on ER stress in HCC up to December 31, 2023 were searched and downloaded from the Science Citation Index-Expanded (SCIE) of the Web of Science Core Collection (WoSCC), Pubmed, Scopus and Embase databases. Using CiteSpace 6.2.R6, VOSviewer 1.6.19, Scimago Graphica and Microsoft Office Excel 2019, the knowledge networks of a variety of countries, regions, authors, references, keywords and journals were analyzed. Results: A total of 1239 publications were retrieved, including 843 articles and 396 review articles. The number of global publications is increasing every year, with the majority of publications coming from China and the USA. Ih-Jen Su, Wenya Huang and Wei Wei are the top 3 prolific authors. “Progression”, “inflammation”, “cell cycle arrest”, “metabolism”, “snsignaling pathways”, “pathogenesis” and “non-alcoholic fatty liver disease” have emerged as research hotspots in recent years. The journal with the greatest co-citation is Hepatology. Conclusions: Based on current global trends, the total number of publications on ER stress in HCC research will continue to increase, but there is a need for more cooperation between authors and countries/regions. ER stress in HCC will continue to be a research priority.

Introduction: Live tissue training (LTT), use of a living anaesthetized animal to practice surgical skills, is a continuing practice, despite controversy and ethical concern. The scientific literature appears polarized in terms of supporting or refuting the practice. This bibliometric analysis of the literature maps and explores the academic conversation regarding LTT including potential influences associated with authorship. Method: Literature identified via the process conducted during a previously published systematic review was used for analysis. 84 literature sources were included. Bibliometric data were manually extracted for analysis, and visually mapped. Results: The scientific conversation about LTT use in trauma is centered on surgery, trauma and emergency medicine specialties, published in clinical journals, with significant influence noted from military authors and organizations. Few authors published work in simulation or education-based journals. Publications are considered to be generally supportive of, or ambivalent to, the use of LTT; those with notable objections to LTT tended to be affiliated to animal activist organizations. Conclusion: There is academic conversation apparent within the literature, in the form of citations, although this is used to affirm or rebuke a given perspective, rather than engage with, or learn from, the content. There is potential benefit to increased interactivity between researchers. The conversation could also be informed by authors broadening the outlook to wider medical educational literature and other disciplines, rather than focusing on application to clinical training, to improve trauma education for all, regardless of modality.