Artículo

Evolutionary Trend Analysis of Research on Immunotherapy for Brain Metastasis Based on Machine-Learning Scientometrics

Resumen

Brain metastases challenge cancer treatments with poor prognoses, despite ongoing advancements. Immunotherapy effectively alleviates advanced cancer, exhibiting immense potential to revolutionize brain metastasis management. To identify research priorities that optimize immunotherapies for brain metastases, 2164 related publications were analyzed. Scientometric visualization via R software, VOSviewer, and CiteSpace showed the interrelationships among literature, institutions, authors, and topic areas of focus. The publication rate and citations have grown exponentially over the past decade, with the US, China, and Germany as the major contributors. The University of Texas MD Anderson Cancer Center ranked highest in publications, while Memorial Sloan Kettering Cancer Center was most cited. Clusters of keywords revealed six hotspots: ‘Immunology’, ‘Check Point Inhibitors’, ‘Lung Cancer’, ‘Immunotherapy’, ‘Melanoma’, ‘Breast Cancer’, and ‘Microenvironment’. Melanoma, the most studied primary tumor with brain metastases offers promising immunotherapy advancements with generalizability and adaptability to other cancers. Our results outline the holistic overview of immunotherapy research for brain metastases, which pinpoints the forefront in the field, and directs researchers toward critical inquiries for enhanced mechanistic insight and improved clinical outcomes. Moreover, governmental and funding agencies will benefit from assigning financial resources to entities and regions with the greatest potential for combating brain metastases through immunotherapy.
de Oliveira Dias, Kalina Coeli Costa (57219159963); de Souza Batista, Patrícia Serpa (57219157934); Fernandes, Maria Andréa (57212429703); Zaccara, Ana Aline Lacet (55972735100); de Oliveira, Thaís Costa (57219165216); de Vasconcelos, Monica Ferreira (55843696600); de Magalhães Oliveira, Amanda Maritsa (57219159688); de Andrade, Fernanda Ferreira (57219157064)
Dissertations and theses on palliative care in pediatric oncology: a bibliometric study; [Dissertações e teses sobre cuidados paliativos em oncologia pediátrica: estudo bibliométrico]; [Tesis de maestría y doctorado sobre cuidados paliativos en oncología pediátrica: estudio bibliométrico]
2020
10.37689/ACTAAPE/2020AO02642
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091521290&doi=10.37689%2fACTAAPE%2f2020AO02642&partnerID=40&md5=1c496b1635900cd1f2eeb5fc23c080c3
All Open Access; Gold Open Access
Scopus
Artículo obtenido de:
Scopus
Fuente
4 1 voto
Califica el artículo
Campus Samborondón
Vía Samborondón Km. 13.5
Call Center: 5150400
metricas@ecotec.edu.ec
Facebook Instagram Youtube

Mapa del sitio