Artículo

Global scientific trends on exosomes therapy for osteoporosis from 2004 to 2023: A bibliometric and visualized analysis

Resumen

Background: Exosomes have emerged as pivotal mediators in modulating physiological and pathological processes implicated in osteoporosis (OP) through their distinctive mode of intracellular communication. The use of exosomes has evoked considerable interest, catalyzing a surge in research endeavors on a global scale. This study endeavors to scrutinize contemporary landscapes and burgeoning trends in this realm. Methods: The Web of Science Core Collection was used to retrieve publications on exosomes therapy for OP within the time frame of January 1, 2004 to December 31, 2023. The bibliometric methodology was applied to study and index the collected data. VOSviewer and citespace software were used to conduct visualization, co-authorship, co-occurrence, and publication trend analyses of exosome therapy in OP. Results: A total of 610 publications (443 articles and 167 reviews) from 51 countries and 911 institutions were included in this study. Shanghai Jiao Tong University, Central South University, Sichuan University, and Zhejiang University are leading research institutions in this field. Stem Cell Research Therapy published the highest number of articles and has emerged as the most cited journal. Of the 4077 scholars who participated in the study, Xie, Hui, Zhang, Yan, Tan, and Yi-Juan had the largest number of articles. Furthermore, according to the cluster analysis of external keywords, future research hotspots can be categorized into 3 directions: research status of exosomes for the treatment of OP, treatment of OP through exosome-regulated signaling pathways, and exosomes as targeted drug delivery systems. Conclusion: This study suggests that the number of future publications on exosome therapy for OP will increase, with a focus on fundamental investigations into drug-loading capacities and molecular mechanisms. In summary, this study presents the first systematic bibliometric analysis of exosome therapy publications in OP, providing an objective and comprehensive overview of the field and a valuable reference for researchers in this domain.
Carrasco, Ingrid Bravo (58283373900); Riquelme-Mella, Enrique (58415000900); Saldivia, Ximena Gutiérrez (58505202000); Fuentes-Vilugrón, Gerardo (57224782844)
Education of the Affective Ideal in Contexts of Cultural Diversity: BIBLIOMETRIC and Thematic Analysis (2006-2021)
2023
10.15379/ijmst.v10i2.1391
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165695711&doi=10.15379%2fijmst.v10i2.1391&partnerID=40&md5=159bc31bf0db6c44b3a219b898c273c8
Universidad del Bio Bio, Chile, Universidad de Concepción, Chile; Facultad de Educación, Núcleo de Estudios Interétnicos e Interculturales (NEII), Universidad Católica de Temuco, Chile; Facultad de Ciencias Sociales, Carrera de Psicología, Universidad Santo Tomas, Chile; Universidad Católica de Temuco, Chile; Facultad de Educación, Carrera de Pedagogía en Educación Física, Universidad Autónoma de Chile, Chile
All Open Access; Bronze Open Access
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