Artículo

Global research states and trends of micro RNA in irritable bowel syndrome: a bibliometric analysis

Resumen

Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, but its diagnosis and treatment remain obscure. Non-coding RNAs (ncRNAs), as potential biomarkers, have attracted increasing attention in digestive diseases. Here, we present a comprehensive research status, development trends, and valuable insights in this subject area. The literature search was performed using Web of Science Core Collection. VOSviewer 1.6.20, Citespace 6.2.R4, and Microsoft Excel 2021 were used for bibliometric analysis. A total of 124 articles were included in the analysis. Overall, publication patterns fluctuated. Globally, People’s Republic of China, the USA, and Germany were the top three contributors of publications. Guangzhou University of Chinese Medicine, University of California, Mayo Clinic, and University of California, Los Angeles contributed the highest number of publications. The pathways and specific mechanisms by which ncRNAs regulate transcription and translation and thus regulate the pathophysiological processes of IBS are the main research hotspots in this field. We found that microRNA (miRNAs) are intricately involved in the regulation of key pathologies such as viscera sensitivity, intestinal permeability, intestinal mucosal barrier, immunoinflammatory response, and brain-gut axis in the IBS, and these topics have garnered significant attention in research community. Notably, microecological disorders are also associated with IBS pathogenesis, and ncRNA may play an important role in the interactions between host and intestinal flora. This is the first bibliometric study to comprehensively summarize the research hotspots and trends related to IBS and ncRNAs (especially miRNAs). Our findings will help understand the role of ncRNAs in IBS and provide guidance to future studies.
Chen, Hongxiu (58170354000); Xu, Zhifang (57216277857); Zhao, Honggang (59203769500); Cao, Jiazhen (57220892071); Wang, Rui (59204919100); He, Jing (58170400800); Nie, Ru (59203769600); Jia, Jialin (59204345500); Yuan, Shuting (59204919200); Li, Yonghong (59204538200); Liu, Zhicheng (59204156700); Zhang, Xinyu (59204919300); Ha, Lijuan (55829170300); Xu, Xiaoru (57216350310); Li, Tie (56329422300)
Global research states and trends of micro RNA in irritable bowel syndrome: a bibliometric analysis
2024
10.1007/s10238-024-01396-y
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197559885&doi=10.1007%2fs10238-024-01396-y&partnerID=40&md5=ba0b39c9da8f751f746ba5b266a4d95d
College of Acupuncture and Tuina, Changchun University of Chinese Medicine, No. 1035, Boshuo Rd, Jingyue Economic Development District, Changchun, 130117, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, No. 10, Poyang Lake Road, West District, Tuanbo New Town, Jinghai District, Tianjin, 301617, China; Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, No. 10, Poyang Lake Road, West District, Tuanbo New Town, Jinghai District, Tianjin, 301617, China; Shenzhen Hospital of Integrated Chinese and Western Medicine, 528 Xinsha Road, Shajing Street, Baoan District, Shenzhen, China
All Open Access; Hybrid Gold Open Access
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