Artículo

Global research trends in precision-targeted therapies for systemic lupus erythematosus (2003–2023): A bibliographic study

Resumen

Background Systemic lupus erythematosus (SLE) is a persistent inflammatory disease caused by an autoimmune response that predominantly affects multiple organs and systems. Growing evidence highlights the critical role of precision-targeted therapies in the management of SLE. Surprisingly, only a handful of bibliometric studies have thoroughly assessed this area. This study attempts to assess the global landscape of literature output and research trends related to precision-targeted therapy for SLE. Method Publications related to precision-targeted therapy for SLE from 2003 to 2023 were searched in the Web of Science Core Collection (WoSCC) database. VOSviewers, CiteSpace and the R package “bibliometrix” were used to perform this bibliometric analysis. Results A total of 3700 papers were retrieved, showing a steady annual increase in publications from 2003 to 2022. The United States led the field with the highest number of papers (36.1 %) and secured the top position in terms of citation frequency (59,889) and H-index (115). Anhui Medical University System claimed the top spot with an impressive output of 70 papers. Principal investigators Tsokos, George C. C., and Lu, Qianjin led the research effort. Among the journals, Frontiers in Immunology stood out, publishing the highest number of articles with 191. In particular, precision-targeted therapy for SLE has become a major research focus in recent years, covering aspects such as T cells, B cells, oxidative stress, remission, and PHASE-III. Conclusion This bibliometric study of ours systematically analyses research trends in precision targeted therapy for systemic lupus erythematosus, and this information identifies the research frontiers and hot directions in recent years and will serve as a reference for scientists working on targeted therapies.
Yuan, Zengze (59194909900); Zhang, Weiqing (59195291500); Jin, Zhaokai (59194358500); Wang, Yihan (57768367400); Lin, Zhiting (59195101700); Xie, Zhimin (57687014400); Wang, Xinchang (57215938256)
Global research trends in precision-targeted therapies for systemic lupus erythematosus (2003–2023): A bibliographic study
2024
10.1016/j.heliyon.2024.e33350
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197054734&doi=10.1016%2fj.heliyon.2024.e33350&partnerID=40&md5=02749ddbfa40e4e0abb8b2163a637700
The Second Clinical College of Zhejiang University of Traditional Chinese Medicine, HangZhou, China; The First Clinical College of Zhejiang University of Traditional Chinese Medicine, HangZhou, China; The Second Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, HangZhou, China
All Open Access; Gold Open Access
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