Artículo

Advances in Breast Cancer Management and Extracellular Vesicle Research, a Bibliometric Analysis

Resumen

Extracellular vesicles transport variable content and have crucial functions in cell–cell communication. The role of extracellular vesicles in cancer is a current hot topic, and no bibliometric study has ever analyzed research production regarding their role in breast cancer and indicated the trends in the field. In this way, we aimed to investigate the trends in breast cancer management involved with extracellular vesicle research. Articles were retrieved from Scopus, including all the documents published concerning breast cancer and extracellular vesicles. We analyzed authors, journals, citations, affiliations, and keywords, besides other bibliometric analyses, using R Studio version 3.6.2. and VOSviewer version 1.6.0. A total of 1151 articles were retrieved, and as the main result, our analysis revealed trending topics on biomarkers of liquid biopsy, drug delivery, chemotherapy, autophagy, and microRNA. Additionally, research related to extracellular vesicles in breast cancer has been focused on diagnosis, treatment, and mechanisms of action of breast tumor-derived vesicles. Future studies are expected to explore the role of extracellular vesicles on autophagy and microRNA, besides investigating the application of extracellular vesicles from liquid biopsies for biomarkers and drug delivery, enabling the development and validation of therapeutic strategies for specific cancers.
Autores
Teles, RHG; Yano, RS; Villarinho, NJ; Yamagata, AS; Jaeger, RG; Meybohm, P; Burek, M; Freitas, VM
Título
Advances in Breast Cancer Management and Extracellular Vesicle Research, a Bibliometric Analysis
Afiliaciones
Universidade de Sao Paulo; University of Wurzburg
Año
2021
DOI
10.3390/curroncol28060382
Tipo de acceso abierto
gold, Green Published
Referencia
WOS:000736639700001
Artículo obtenido de:
WOS
Fuente
0 0 votos
Califica el artículo
Subscribirse
Notificación de
Campus Samborondón
Vía Samborondón Km. 13.5
Call Center: 5150400
metricas@ecotec.edu.ec
Facebook Instagram Youtube

Mapa del sitio