Artículo

Global perspectives and hotspots of VEGF signaling pathway in liver disease from 2008 to 2023: A bibliometric analysis and visualization

Resumen

Background: The vascular endothelial growth factor (VEGF) signaling pathway is closely related to pathological angiogenesis in liver disease. Anti-angiogenesis is an effective intervention in the clinical treatment of liver disease. Some antiangiogenic drugs are resistant and have limitations in clinical use. Methods: This research uses bibliometric methods to assess the literature on the VEGF signaling pathway in liver disease from 2008 to 2023. Results: The number of publications has generally increased over the past 16 years, meaning that enormous researchers are interested in this field. China and the USA have published the most articles and cooperate closely with each other. Plos one has published the largest number of articles in this area, and Hepatology and Journal of Hepatology is the most authoritative journal. Llovet JM is an outstanding researcher in the field with the highest citations. Keywords and research hotspots analysis indicated that researchers are very concerned about the application and clinical research status of anti-angiogenic drugs in hepatocellular carcinoma (HCC). Continuing to deepen the research on the use of anti-angiogenic drugs alone and in combination is necessary. In addition, the resistance of anti-angiogenic therapeutic drugs leads to a complex mechanism of angiogenesis response caused by hypoxia, which requires further research. Conclusions: This study analyzed the research situation related to the VEGF signaling pathway in liver disease from a bibliometric and visual perspective. Our analysis helps researchers better understand the research directions and hotspots in this area, enabling them to better carry out research in the future.
Bulto, Tadesse Weyuma (57218921685); Chebo, Abdella Kosa (57211658384); Regassa, Hailu Fufa (59527811700); Werku, Birhanu Chalchisa (57793656500); Kloos, Helmut (26643043000)
Scientific mapping of the nexus between entrepreneurial orientation and environmental sustainability: bibliometric analysis
2024
10.3389/fsoc.2024.1461840
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216004215&doi=10.3389%2ffsoc.2024.1461840&partnerID=40&md5=eb475c40557b00c5f84aa42ba2e3e68d
Department of Management, Kotebe University of Education, Addis Ababa, Ethiopia; Department of Business Management, University of Johannesburg, Johannesburg, South Africa; Department of Sociology, Ambo University, Oromia, Ethiopia; Faculty of Resource Management and Economics, Wollega University, Nekemte, Ethiopia; Department of Rural Development and Agricultural Extension, Jimma University, Jimma, Ethiopia; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, United States
All Open Access; Gold Open Access
Scopus
Artículo obtenido de:
Scopus
Fuente
0 0 votos
Califica el artículo
Subscribirse
Notificación de
Campus Samborondón
Vía Samborondón Km. 13.5
Call Center: 5150400
metricas@ecotec.edu.ec
Facebook Instagram Youtube

Mapa del sitio