Artículo

Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study

Resumen

Manufacturing bioactive materials for drug delivery involves developing materials that interact with biological tissues to release drugs in a controlled and targeted manner. The goal is to optimize therapeutic efficacy and reduce side effects by combining knowledge from materials engineering, biology, and pharmacology. This study presents a detailed bibliometric analysis, exploring the keywords “manufacturing,” “bioactive materials,” and “drug delivery” to identify and highlight significant advancements in the field. From the Web of Science, 36,504 articles were analyzed, with 171 selected for a deeper analysis, identifying key journals, countries, institutions, and authors. The results highlight the field’s interdisciplinary nature, with keywords grouped into four main themes, including regenerative medicine, scaffolds, three-dimensional (3D) printing, bioactive glass, and tissue engineering. Future research in this area will focus on more effective and precise systems using technologies like 3D printing and nanotechnology to enhance the customization and control of drug release, aiming for more efficient and targeted therapies.
Melo, Rafael Leandro Fernandes (58236117400); Nascimento Dari, Dayana (58923887100); da Silva Aires, Francisco Izaias (59415870800); Simão Neto, Francisco (57219870933); Freire, Tiago Melo (57189841703); Fernandes, Bruno Caio Chaves (57205127738); Fechine, Pierre Basílio Almeida (6506816161); Soares, João Maria (12902632400); Sousa dos Santos, José Cleiton (56962733600)
Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study
2025
10.1021/acsomega.4c08669
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85215005320&doi=10.1021%2facsomega.4c08669&partnerID=40&md5=993be7aec1eb952fb4683e4a3593b62d
Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal do Ceará, Campus do Pici, Bloco 729, CE, Fortaleza, CEP 60440-554, Brazil; Grupo de Química de Materiais Avançados (GQMat), Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Campus do Pici, CE, Fortaleza, CEP 60451-970, Brazil; Grupo de Engenharia e Desenvolvimento Sustentável (GENES), Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Campus das Auroras, CE, Redenção, CEP 62790-970, Brazil; Departamento de Engenharia Química, Universidade Federal do Ceará, Campus do Pici, Bloco 709, CE, Fortaleza, 60455-760, Brazil; Departamento de Agronomia e Ciência Vegetais, Universidade Federal Rural do Semi-Árido, Campus Mossoró, RN, Mossoró, CEP 59625-900, Brazil; Departamento de Física, Universidade do Estado do Rio Grande do Norte, Campus Mossoró, RN, Mossoró, CEP 59610-090, Brazil
All Open Access; Gold Open Access
Scopus
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