Artículo

Current status of FAP-directed cancer theranostics: a bibliometric analysis

Resumen

Fibroblast activation protein (FAP) is a key molecule in the field of oncology, with significant impacts on tumor diagnosis and treatment. Importantly, it has paved the way for the development of radiotracers for quinoline-based FAP inhibitors (FAPIs), which are currently among the most promising radiotracers for PET imaging in cancer. We performed a bibliometric analysis of scientific publications related to FAP and FAPI-based radiotracers, which included the quantification and visualization of current research trends and prospects based on various bibliometric indicators. In our survey of FAP-related studies in the Web of Science Core Collection databases, R and VOSviewer were used for visualization and bibliometric analyses based on country, institute, author, journal, and keywords We also examined the methodology, radionuclide type, imaging instruments, and major diseases associated with studies on FAPI-based radiotracers. The results revealed 2,664 FAP-related publications from 1992 to the present. Germany, the USA, and China dominated paper publications, multinational collaborations, and societal impacts on FAP research. Southwest Medical University was the most productive institute, while Haberkorn Uwe authored the most cited papers and the highest H-index. The European Journal of Nuclear Medicine and Molecular Imaging and the Journal of Nuclear Medicine were the most influential periodicals. Keywords “FAP”, “68Ga-FAPI”, and “PET/CT” emerged as the most significant in this field. This study may help elucidate current research trends, hotspots, and directions for future research.
Pessin, Vilker Zucolotto (57696881500); Santos, Celso Alberto Saibel (55430678200); Yamane, Luciana Haure (58582880800); Siman, Renato Ribeiro (57211910057); Baldam, Roquemar de Lima (57556711100); Júnior, Valdemar Lacerda (57217776461)
A method of Mapping Process for scientific production using the Smart Bibliometrics
2023
10.1016/j.mex.2023.102367
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85171335484&doi=10.1016%2fj.mex.2023.102367&partnerID=40&md5=444d5e65234fa297fcb01e070cdb3b36
Department of Informatics, Federal University of Espírito Santo, Av. Fernando Ferrari, 514, Espírito Santo, Vitória, 29075-910, Brazil
All Open Access; Green Open Access
Scopus
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