Artículo

Bipolar disorder and oxidative stress: A bibliometric perspective

Resumen

Objective: Accumulating evidence indicates that oxidative stress and the disruptionof antioxidant defenses play an important role in the neurobiology of bipolar disorder(BD). Studies have found that increased oxidative stress may be associated with cellapoptosis and neuronal damage in BD patients. Hence, this study explored theresearch field related to BD and oxidative stress from a bibliometrics perspective. Methods: Literature search and relevant data retrieval based on the Web of SciencesCore Collection (WoSCC). R software (version 4.2.2), VOSviewer software (version1.6.18), and CiteSpace (version 6.1.6) were used in this bibliometric analysis. Results: A total of 2081 publications related to BD and oxidative stress were pub-lished between 1986 and 2024. Bipolar Disorders was the journal that had the mostpublications in this area (72; 3.46%; IF = 5.9), while the United States (1285; 61.7%)and the University of Toronto (377; 18.1%) were the most productive country andinstitution, respectively. Apart from “oxidative stress” and “bipolar disorder,” the most frequently used keywords were “schizophrenia,” “prefrontal cortex,” and “nitricoxide.” Conclusions: The growing number of publications related to BD and oxidative stressin recent years highlights the importance of this research field. Hot topics in researchrelated to BD and oxidative stress included animal experiments and molecular mecha-nisms, psychiatric-related inflammation and biomarkers, neurodegenerative diseases,and metabolism. Furthermore, the biological mechanisms of BD, particularly bio-markers and inflammation, may be the emerging research priority area in the future.
Gui, Zhen (57225072027); Zhang, Qinge (59185742100); Sha, Sha (56921623900); Li, Xiao-Hong (57194607404); Su, Zhaohui (57212560726); Cheung, Teris (56828857900); Cui, Xi-Ling (54384966900); Ungvari, Gabor S. (7006092063); Wong, Katrine K. (56305094900); Ng, Chee H. (57217075868); Yuan, Feng (57244024600); Xiang, Yu-Tao (35241398400)
Bipolar disorder and oxidative stress: A bibliometric perspective
2024
10.1111/appy.12564
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201123487&doi=10.1111%2fappy.12564&partnerID=40&md5=cacb7df30b133dab830a436abb4bdbfe
Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, University of Macau, Macao; Centre for Cognitive and Brain Sciences, University of Macau, Macao; Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China; Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing, China; School of Public Health, Southeast University, Nanjing, China; School of Nursing, Hong Kong Polytechnic University, Hong Kong; Department of Business Administration, Hong Kong Shue Yan University, Hong Kong; Section of Psychiatry, University of Notre Dame Australia, Fremantle, Australia; Division of Psychiatry, School of Medicine, University of Western Australia, Perth, Australia; Faculty of Arts and Humanities, University of Macau, Macao; Department of Psychiatry, The Melbourne Clinic and St Vincent’s Hospital, University of Melbourne, Richmond, VIC, Australia
All Open Access; Hybrid Gold Open Access
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