Artículo

A Bibliometric Analysis of the Gene Delivery Systems for Lung Cancer from 2010 to 2022

Resumen

The gene delivery systems (GDS) for lung cancer (LC) has made significant progress over the past 12 years, yet, there is a great challenge in its clinical application due to low delivery efficiency. This study aims to explore research fields related to gene therapy for LC and predict future directions from a bibliometric perspective. The Web of Science Core Collection collects articles and reviews on GDS for LC published from 2010 to 2022. Comprehensive bibliometric and visual analyses were performed using CiteSpace, VOSviewer, R-Bibliometrix, and Microsoft Excel. The analysis showed that the number of publications on GDS for LC has been increasing over the past 12 years, highlighting the growing interest and research efforts in this area. A rigorous examination of keywords and research hotspots revealed that the themes such as “complex,” “transfection,” “RNA interference,” “extracellular vesicle,” “co-deliver,” “resistance,” etc. dominate the field of GDS for LC. These findings indicated that the research in GDS for LC is evolving, with a noticeable shift toward addressing challenges related to delivery efficiency, transfection methods, and overcoming resistance mechanisms in gene therapy. The comprehensive study provides an overview of the literature on GDS for LC and identifies areas that require further exploration and development. By highlighting emerging research hotspots, our bibliometric analysis offers valuable insights to scholars and researchers, aiding in the identification of gaps, and guiding future efforts toward the development of GDS with more efficiency for LC therapy.
Wu, Kexin (58111668400); Ren, Fang (58727613400); Zhou, Lu (59233331400); Xing, Yangchen (59232815600); Zhang, Qianyu (57212800145); Chen, Huali (36672729000)
A Bibliometric Analysis of the Gene Delivery Systems for Lung Cancer from 2010 to 2022
2024
10.1055/s-0044-1786042
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199538125&doi=10.1055%2fs-0044-1786042&partnerID=40&md5=5ffe14920b70b7cdec1114b8bf46bbe2
Department of Pharmaceutics, College of Pharmacy, Chongqing Medical University, Chongqing, China
All Open Access; Gold Open Access
Scopus
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